β-cell dedifferentiation prior to insulitis prevents T1DM
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چکیده
منابع مشابه
Resveratrol Prevents β-Cell Dedifferentiation in Nonhuman Primates Given a High-Fat/High-Sugar Diet
Eating a "Westernized" diet high in fat and sugar leads to weight gain and numerous health problems, including the development of type 2 diabetes mellitus (T2DM). Rodent studies have shown that resveratrol supplementation reduces blood glucose levels, preserves β-cells in islets of Langerhans, and improves insulin action. Although rodent models are helpful for understanding β-cell biology and c...
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ژورنال
عنوان ژورنال: Nature Reviews Endocrinology
سال: 2020
ISSN: 1759-5029,1759-5037
DOI: 10.1038/s41574-020-0358-4